Market Report Source

Overview

Profound changes are happening in the animal health market. Pet owners in the United States are demanding more advanced and expensive treatments for companion animals, driving growth in the companion-animal sector. At the same time, concerns about livestock health care and feeding are driving changes in industrial animal husbandry. This TriMark Publications report offers a broad, yet detailed, overview of the shape of the veterinary health products market over the next several years. Examining both livestock and companion-animal markets. The overall market for veterinary therapeutics and diagnostic products has grown dramatically.

This report analyzes the U.S. veterinary pharmaceuticals and diagnostics markets. The report outlines market size, market growth, forecasts, and competitive information. Focusing both on companion (pet) animal markets and agricultural livestock, the report examines the markets for pharmaceuticals, vaccines, diagnostics, and feed additives. The study reveals: the size of the markets for companion-animal products, broken down by type of animal (i.e., cats, dogs, small animals, etc.); size of the markets for livestock products; how the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) regulations impact these markets; the identity of the top market players, along with their market shares and future prospects; how the antibiotic feed additive controversy is influencing the agricultural market; and key players in the veterinary pharma and diagnostic markets.

Table of Contents

1. Overview 6
1.1 Objective of Report 6
1.2 Scope of Report 6
1.3 Methodology 7
1.4 Executive Summary 8

2. Veterinary Biological Products 10
2.1 Overview of Health Products Market 10
2.1.1 World Products Markets 10
2.1.2 U.S. Animal Health Products Market 12
2.1.3 European Animal Health Markets 12
2.1.4 Asian Animal Health Products Markets 13
2.1.5 World Market Share 14
2.1.6 Common Animal Diseases 14
2.1.7 Companion Animals 38
2.2 Veterinary Vaccines 40
2.2.1 Major Canine Vaccines 42
2.2.2 Major Feline Vaccines 44
2.3 Agricultural Animals 46
2.3.1 Major Cattle Vaccines 47
2.3.2 Major Poultry Vaccines 53
2.3.3 Major Sheep Vaccines 58
2.3.4 Major Swine Vaccines 61
2.3.5 Horses 66
2.4 Trends in the Biologicals Market 68
2.5 Nutraceuticals 68
2.5.1 Nutraceutical Market for Companion Animals 69
2.6 OTC Animal Health Global Market Opportunity 69

3. Veterinary Pharmaceutical Products 71
3.1 Overview 71
3.1.1 Pharmaceutical Products for Dogs and Cats 76
3.1.1.1 Antiparasites 79
3.1.1.2 Antibiotics 80
3.1.1.3 Anti-Inflammatories 83
3.1.1.4 Chronic Care Products 86
3.1.1.5 Cardiovasculars 86
3.1.1.6 GI Products 87
3.1.1.7 Endocrine Products 87
3.1.1.8 Anti-Infectives 88
3.1.1.9 Behavior Modifiers 89
3.1.1.10 Anthelmimetics 90
3.1.1.11 Antifungals 91
3.1.2 Pharmaceutical Products for Agricultural Animals 91
3.1.2.1 Antiparasites 91
3.1.2.2 Antibiotics 92
3.1.2.3 Insecticides 93
3.2 Leading Products and Competitors 94
3.2.1 Elanco 94
3.2.2 Novartis 95
3.2.3 Alpharma 96
3.2.4 Wyeth 97
3.2.5 Pfizer Animal Health 97
3.3 Veterinary Pharmaceutical Market Trends 98
3.4 Companion-Animal Crossover Products 98
3.5 Generics in the Animal Health Sector 99

4. Veterinary Feed Additive Products 100
4.1 Overview 100
4.2 U.S. Feed Additives Market 102
4.3 Leading Feed Additives and Competitors 102
4.4 Feed Additives Market Trends 104
4.4.1 Livestock Performance Enhancers 104
4.5 Pet Food Additives and Contaminants 106
4.5.1 Pet Deaths 106
4.5.2 The FDA Response 106

5. Veterinary Diagnostic Test Products 107
5.1 Introduction 107
5.2 Veterinary Diagnostic Market Size and Growth Rates 108
5.2.1 Market Drivers 110
5.2.2 Immunodiagnostic and Nucleic Acid Testing Markets 111
5.2.2.1 Market Size and Growth 111
5.2.3 Technological Developments in the Diagnostic Industry 111
5.3 Competitive Situation 112
5.4 Estimate of Units Sold and Pricing 113
5.5 PCR Applications for Veterinary Use 113
5.6 Companion-Animal Diagnostics 117
5.6.1 Feline Leukemia Virus 117
5.7 Agricultural Animal Diagnostics 118
5.8 U.S. Diagnostic Test Market 119
5.9 Leading Competitors in Diagnostic Testing 120
5.10 Veterinary Diagnostic Market Trends 123
5.11 Collaborative Licensing 124
5.12 BSE Diagnostic Tests 124
5.13 West Nile Virus Diagnostic Tests 124
5.14 Avian Flu Diagnostic Tests 125

6. Overview of the Veterinary Health Market 126
6.1 Regulatory Environment 126
6.1.1 Regulation of Animal Health Products in the E.U. 127
6.1.2 Regulation of Animal Health Products in Japan 129
6.1.2.1 Regulatory Environment 129
6.1.2.2 Withdrawal Periods 130
6.1.2.3 Filing Procedures for New Animal Drug Applications 130
6.1.2.4 Use of Outdated Animal Studies 130
6.1.2.5 Brand-Specific Listing for Antimicrobial Antibiotic and Other Feed Additives 130
6.1.3 Proposed Regulation of Animal Antibiotics 130
6.2 The European Animal Health Industry 131
6.2.1 Trends Driving Demand 131
6.2.1.1 European, International and U.S. Oversight of Veterinary Medicines 131
6.2.1.2 Antibiotic Usage 132
6.3 Mergers and Acquisitions 132
6.4 New Product Launches 133
6.5 Bioterrorism and Foodborne Pathogens„oWHO Guidelines 134
6.6 Generic Products 135

7. Emerging Markets 137
7.1 Biotechnology and Veterinary Health 137
7.1.1 Biotechnology and Biologics 137
7.1.1.1 Recombinant DNA Vaccines 137
7.1.1.2 Plant-Derived Vaccines 137
7.1.2 DNA Probes 138
7.1.3 Biotechnology and Pharmaceuticals 138
7.1.3.1 Immune System Augmentation 138
7.1.3.2 Growth Enhancers 139
7.2 Impact of Genomics on Veterinary Health 139
7.2.1 Autosomal Dominant Traits 141
7.2.2 X-Linked Traits 142
7.2.3 Autosomal Recessive Traits 142
7.2.4 Current DNA Testing in Animals 144
7.2.5 Direct DNA Testing: Mutation-Based Tests 144
7.2.6 Indirect DNA Testing: Linkage-Based or Marker-Based Tests 145
7.3 Companion-Animal Markets 145
7.4 Alternative Medicine in Veterinary Practice 145

8. Company Profiles 146
8.1 Abaxis, Inc. 146
8.2 Abbott Laboratories 148
8.3 Adiagene 148
8.4 Agricultural Research Service 149
8.5 Alpharma, Inc. 149
8.6 Avian Biotech 153
8.7 BASF Agricultural Products and Nutrition 153
8.8 Bayer Animal Health 154
8.9 Biobest Diagnostics 155
8.10 BioVet, Inc. 155
8.11 Boehringer Ingelheim Corp. 156
8.12 Cypress Diagnostics 157
8.13 DayMoon Industries, Inc. 158
8.14 Dow AgroSciences LLC 159
8.15 Dupont Qualicon 159
8.16 Elanco Animal Health 160
8.17 Fort Dodge Animal Health 160
8.18 Gene Check, Inc. 161
8.19 Gene-Trak 161
8.20 Heska Animal Health 162
8.21 IDEXX Laboratories, Inc. 164
8.22 IGEN International, Inc. 167
8.23 IMC Global, Inc. 167
8.24 Intervet International 169
8.25 IVAX Corporation 169
8.26 Laboklin 170
8.27 Medigenomix GmbH 170
8.28 Merial Animal Health 170
8.29 Microbix Biosystems, Inc. 171
8.30 Monsanto 172
8.31 Novartis Animal Health 173
8.32 OptiGen 174
8.33 PE AgGen/Celera AgGen 175
8.34 PETCO Animal Supplies, Inc. 176
8.35 PetSmart, Inc. 176
8.36 Pfizer Animal Health 177
8.37 Roche Animal Nutrition and Health 182
8.38 Sanofi-Aventis 183
8.39 Schering-Plough Animal Health Corporation 184
8.40 Synbiotics Corporation 185
8.41 VCA Antech, Inc. 187
8.42 Virbac SA 188
8.43 Wyeth 189

9. Business Trends in the Industry 190
9.1 Animal Health Additive Growth Trends 190
9.2 Move to Complete Product Portfolio 190
9.3 Reduced Antibiotic Usage in Animal Feeds 190
9.4 European Animal Health Industry 190
9.5 Licensing and Partnership Opportunities in Animal Health R&D 191

10. Company Directory 192

Appendix 1: Dosages for Selected Drugs Alphabetical Listing 195

Appendix 2: Trade Names 208

Appendix 3: Nomenclature 220

INDEX OF FIGURES
Figure 2.1: Worldwide Sales of Animal Health Products Market by Product Class, 2006 11
Figure 2.2: Worldwide Animal Health Products Market by Region, 2006 11
Figure 2.3: U.S. Companion Animal Healthcare Products Share of Overall Animal Health Product Sales, 2006 12
Figure 3.1: Novartis Business Split 95
Figure 3.2: Novartis Product Split 95
Figure 3.3: Novartis Geographic Split 96
Figure 4.1: Global Market for Livestock Performance Enhancers, 2006 105

LIST OF TABLES
Table 2.1: World Market for Animal Health Products, 2004-2012 10
Table 2.2: Global Sales of Animal Health and Nutrition Products, 2004-2012 10
Table 2.3: Worldwide Animal Health Products Market by Region, 2006 11
Table 2.4: U.S. Animal Health Product Sales, 2005-2012 12
Table 2.5: Japanese Animal Health Market, 2000-2012 13
Table 2.6: Chinese Animal Health Products Market, 2005-2012 14
Table 2.7: Worldwide Animal Health Product Sales for Leading Producers, 2006 14
Table 2.8: List A Diseases 15
Table 2.9: List B Diseases 15
Table 2.10: Cattle Diseases 16
Table 2.11: Sheep and Goat Diseases 16
Table 2.12: Equine Diseases 17
Table 2.13: Swine Diseases 17
Table 2.14: Avian Diseases 17
Table 2.15: Fish Diseases 18
Table 2.16: Other Veterinary Diseases 18
Table 2.17: Leading Companion-Animal Prescription Drugs by Sales, 2006 38
Table 2.18: Worldwide Veterinary Vaccine Market, 2005-2012 41
Table 2.19: U.S. Veterinary Vaccine Market, 2000-2008 41
Table 2.20: Canine Vaccinations 43
Table 2.21: Dog Vaccine Price List 44
Table 2.22: Global Market for Nutraceutical in Companion Animals, 2005-2012 69
Table 3.1: Veterinary Drugs Listed by Therapeutic Class 71
Table 3.2: Animal Health Product Sales in the U.S., 2000-2008 75
Table 3.3: Sales of Pharmaceutical Products for Animal Health in the U.S., 2000-2008 76
Table 3.4: Number of Dogs in the U.S., 1996, 2001 and 2006 77
Table 3.5: Number of Pet Dogs by Country 77
Table 3.6: Number of Cats in the U.S., 1996, 2001 and 2006 77
Table 3.7: Number of Pet Cats by Country 77
Table 3.8: U.S. Spending on Pet Care, 1996, 2001 and 2006 78
Table 3.9: American Veterinary Board Certified Diplomats 78
Table 3.10: Companion-Animal Products in Excess of $ 1 Billion Sales 78
Table 3.11: U.S. Antiparistic Animal Health Product Sales, 2005-2012 79
Table 3.12: Worldwide Sales of Animal Health Antibiotics, 2005-2012 80
Table 3.13: U.S. Volume of Animal Health Antibiotics Used, 2000-2006 81
Table 3.14: U.S. Sales of Animal Health Antibiotics, 2005-2012 81
Table 3.15: Common Veterinary Anti-Inflammatories 84
Table 3.16: U.S. Pet Anti-Inflammatory Market, 2000-2009 84
Table 3.17: Retail Pricing of Rimadyl 85
Table 3.18: Etogesic Pricing 85
Table 3.19: Bacterial and Protozoal Threats to Poultry 93
Table 3.20: Bacterial and Protozoal Threats to Pigs 93
Table 3.21: Elanco Veterinary Products Summary 94
Table 3.22: Wyeth Fort Dodge Animal Health Products 97
Table 4.1: Sales of Feed Additives for Animal Health in the U.S., 2001-2008 100
Table 4.2: Feed Additives„oAntimicrobials and Growth Promotants 103
Table 4.3: Feed Additives„oAnthelmintics 103
Table 4.4: U.S. Sales of Animal Health Chemicals, 2001-2010 103
Table 4.5: U.S. Beef Exports, 2001-2006 104
Table 4.6: U.S. States Beef Production by State, 2003 104
Table 4.7: Global Market for Livestock Performance Enhancers, 2004-2010 105
Table 5.1: Veterinary Diagnostics World Market, 2005-2012 108
Table 5.2: Veterinary Immunodiagnostic Testing World Markets, 2005-2012 111
Table 7.1: Labs that Perform Canine DNA Testing 142
Table 7.2: DNA (Mutation) Tests for Canine Inherited Diseases 143
Table 7.3: DNA (Marker) Tests for Canine Inherited Diseases 143
Table 8.1: Alpharma Revenue and Operating Income/Loss, 2001-2003 151
Table 8.2: Alpharma Revenue and Operating Income/Loss and Discontinued Operations, 2004-2006 152
Table 8.3: Pfizer Animal Health Products 178
Table 8.4: Pfizer Products Patents 179
Table 8.5: Key Pfizer Animal Health Products 181
Table 8.6: Pfizer Livestock Products 182
Table 8.7: Pfizer Equine Products 182
Table 8.8: Pfizer Companion Animal Products 182
Table 9.1: European Animal Health Market Sales, 2004-2010 191