Market Report Source

Overview

The life science informatics marketplace—known as bioinformatics—is set to expand as high-tech companies infiltrate this arena and biopharmaceutical companies incorporate key informatic solutions into their business strategies. TriMark Publications believes that many of the segments of bioinformatics described in this report offer an unusual opportunity for accelerated expansion within the coming years. This study is arranged to provide an overview of bioinformatics market segments and offer evidence that these segments are poised for significant future growth. Each segment is accompanied by analysis and forecasts by product type and application.

This analysis surveys the bioinformatics market and the latest information regarding emerging new products and industry trends. The study will quantify and qualify the bioinformatics market segments as an area of research, product development and investment. Forecasts of the bioinformatics market and an analysis of products in the worldwide information-processing market will provide a basis for understanding the significance of past developments and future possibilities within this market category. The main objectives of this analysis are as follows:

• Identify viable technology drivers through a comprehensive look at various platform technologies for segments of the bioinformatics market.

• Impart a complete understanding of the chief bioinformatics tools and their predictive, screening, prognostic, monitoring, pharmacogenomic and product value, from basic principles to application.

• Distinguish feasible market opportunities via identifying high-growth applications in different bioinformatics areas, with a focus on the biggest and fastest expanding markets for diagnosis and treatment of diseases.

• Focus on global industry development through an in-depth analysis of the major world markets for bioinformatics, including forecasts for growth.

• Present market figures regarding the current value of the bioinformatics market, projections and growth rates. The source of this information is the most current data derived from the global diagnostic industry.

Table of Contents

1. Overview
1.1 Statement of Report
1.2 Objectives of this Report
1.3 Scope of this Report
1.4 Methodology

2. Introduction
2.1 Global Bioinformatics Products Industry
2.2 Computers and Biology
2.2.1 Bioinformatics and the Internet
2.3 Company Evaluation Overview
2.4 Market Outlook
2.4.1 Competitive Structure
2.5 Applications of Bioinformatics
2.5.1 Healthcare
2.5.2.1 Allocation of R&D
2.5.2.2 Traditional Drug Discovery Process
2.5.2.3 Drug Discovery and Informatics
2.5.2.4 Collaborative Agreements
2.6 The Human Genome Project (HGP)
2.6.1 Goals of the Human Genome Project
2.6.2 Benefits of the Human Genome Project
2.7 Barriers to Entry
2.8 Proteomics and Databases
2.8.1 Protein Database Standards
2.8.2 Future Trends

3. The U.S. Bioinformatics Market
3.1 Overview
3.2 Market Revenue and Growth Forecasts
3.3 Market Drivers

4. Genomics
4.1 The Biotechnology Industry
4.2 The Development of a Genomics Market
4.2.1 Market Drivers
4.2.2 Market Restraints
4.2.3 Market Size and Growth Projections
4.2.4 The U.S. Genomics Market
4.3 Biochips and Microarrays
4.3.1 Key Challenges
4.3.2 Freeware
4.3.3 New Tools
4.4 Bioinformatics
4.5 Disease Targets
4.6 Functional Genomics
4.7 Gene Sequencing
4.8 Gene Sequence Variation Detection
4.9 Comparative Genomics
4.10 Genome Database Arrays
4.11 High-throughput Genomics
4.11.1 High-throughput Technology
4.11.2 Lab on a Chip
4.12 Pharmacogenomics
4.13 Probe Arrays
4.13.1 Gene Expression Monitoring Arrays
4.14 DNA Analysis Arrays
4.15 Proteomics
4.16 Sequencing
4.17 Single Nucleotide Polymorphisms (SNPs)
4.18 Structural Genomics
4.19 Photolithography
4.20 Instrumentation

5. The Bioinformatics Industry
5.1 Definition and Role of Bioinformatics
5.1.1 Bioinformatics Sector Overview
5.1.2 The Future Status of Bioinformatics
5.1.3 Barriers to Growth
5.2 Types of Data and Bioinformatics Applications
5.2.1 Validated Core Modeling Technology
5.2.2 Broad Applicability
5.2.3 Data Management Compliant with Industry Standards
5.2.4 Open Architecture
5.2.5 Ease of Use
5.2.6 Increased Access
5.3 Functions of Informatics Software
5.3.1 Data Management
5.3.2 Data Transformation
5.3.3 Data Collaboration
5.3.4 Interface for Online Data Sources
5.4 Target Markets for Informatics Software
5.5 Steps Involved in Bringing a Drug to Market
5.6 Costs Incurred in Developing a New Drug
5.7 Industry Drivers and Challenges
5.8 Industry Risks
5.9 Products of Bioinformatics
5.10 Bioinformatics Processes
5.11 Informatics Tools and Functionalities
5.11.1 Sequence to Structure
5.11.2 Lead Identification and Optimization
5.11.3 Development and Formulation
5.11.4 Improving Materials and Processes
5.11.5 Other Materials-based Industries
5.12 Role of Bioinformatics in the Biotechnology Value Chain
5.13 Bioinformatics Market Segments
5.13.1 Databases
5.13.2 Hardware
5.13.3 Software
5.13.4 Bioinformatics Services
5.14 Bioinformatics Market Size
5.14.1 Sales and R&D
5.14.2 IT Budget
5.14.3 Projected Bioinformatics Market Size
5.14.4 Bioinformatics Market Components
5.15 Bioinformatics Business Models
5.15.1 Changing Business Models
5.15.2 Competition for Pure Play Informatics Companies
5.15.3 Non-Profit Organizations
5.15.4 In-House Bioinformatics Solutions
5.15.5 Large IT Companies
5.16 Bioinformatics Target Disciplines
5.16.1 Comparative Genomics
5.16.2 Pharmacogenomics
5.16.3 Functional Genomics
5.16.4 Proteomics
5.16.5 Structural Genomics
5.16.6 Image Informatics
5.16.7 Clinical Trial Informatics
5.16.8 Cheminformatics
5.17 Bioinformatics Architecture
5.18 Bioinformatics Applications
5.18.1 Data Search Tools
5.18.2 Data Visualization Tools
5.18.3 Data Mining and Clustering
5.18.4 Enterprise Solutions
5.18.5 Data Warehousing
5.19 Evaluation of Bioinformatics Solutions
5.19.1 Requirements of Study
5.19.2 Shortlisting the Options
5.19.3 Scoring Patterns
5.19.4 Performance
5.19.5 Data Storage
5.19.6 Data Management in Drug Discovery
5.19.7 Key Issues in Bioinformatics Data Storage
5.20 Convergence of Industries
5.21 Proteins as a Driver
5.23 Current Bioinformatics Research
5.24 New Bioinformatics Modeling Algorithms
5.25 3D Modeling
5.26 Patenting Bioinformatics Algorithms

6. Recent Industry Activity: Collaborations and Acquisitions

9. Corporate Profiles
9.1 Accelrys
9.2 Affymetrix, Inc.
9.3 Agencourt Bioscience Corporation
9.4 Agilent Technologies
9.5 AlgoNomics
9.6 ALLEZ Software
9.7 ApoCom Genomics
9.8 Applied Biosystems
9.9 Ariadne Genomics, Inc.
9.10 Array Genetics
9.11 Automated Handling Systems, Inc.
9.12 Avestha Gengraine Technologies Pvt. Ltd.
9.13 Bioalma
9.14 Biobase GmbH
9.15 BioCarta
9.16 Biodatabases (AMITA Corporation)
9.17 BioDiscovery, Inc.
9.18 BioInformatics, LLC
9.19 BioInformatics Services
9.20 BioInformatics Solutions, Inc.
9.21 Biomax Informatics AG
9.22 Bioreason, Inc.
9.23 Biosiris
9.24 BioSoftSolutions
9.25 Biotique Systems, Inc.
9.26 BioWisdom Ltd.
9.27 Bio-Xtal
9.28 Cambridge Antibody Technology
9.29 Cambridge BlueGnome (BlueGnome)
9.30 Capital Genomix
9.31 Celera Genomics
9.32 Cellomics, Inc.
9.33 Cellectis
9.34 CeuticalSoft
9.35 Chemical Computing Group
9.36 Cimarron Software, Inc.
9.37 CLONDIAG Chip Technologies
9.38 CodonCode Corporation
9.39 Cognia Corporation
9.40 CompuDrug
9.41 Compugen Ltd.
9.42 Corimbia
9.43 CSIRO Bioinformatics
9.44 CuraGen Corporation
9.45 CyberGene
9.46 Data Unlimited International
9.47 deCODE Genetics
9.48 Decodon GmbH
9.49 Deltagen, Inc.
9.50 Digilab BioVisioN
9.51 Discovery Partners International, Inc.
9.52 DNA Software, Inc.
9.53 DNAPrint Genomics, Inc.
9.54 DNA Star, Inc.
9.56 DxS Genotyping, Ltd.
9.57 Electric Genetics, Pvt. Ltd.
9.58 Entelos
9.59 Epigenomics, AG
9.60 Epitope Informatics, Ltd.
9.61 e-Proteomics.net
9.62 EraGen Biosciences
9.63 Essential Informatics
9.64 European Bioinformatics Institute (EBI) Industry Programme
9.65 Evolutionary BioInformatics
9.66 Genamics
9.67 Genebio
9.68 Gene Biotechnologies
9.69 GeneData, AG
9.70 Gene-IT
9.71 Gene Logic, Inc.
9.72 GenOdyssee, SA
9.73 Genolyze
9.74 Genomatica
9.75 Genomics Collaborative
9.76 Genomic Solutions Inc.
9.77 Genomining
9.78 Geospiza, Inc.
9.79 Glycominds
9.80 Health Discovery Corporation
9.81 Hitachi Corporate Technology Group
9.82 Improved Outcomes Software, Inc.
9.83 INCOGEN, Inc.
9.84 Incyte Corporation
9.85 Informagen
9.86 Inpharmatica
9.87 Insightful Corporation
9.88 Insilico Software
9.89 Insilicos
9.90 Intrexon Corporation
9.91 Invenio Biosolutions
9.92 Invitrogen Corporation
9.93 IO Informatics
9.94 Kshema Technologies Ltd.
9.95 LabBook
9.96 LabVantage Solutions
9.97 Lifespan Biosciences
9.98 Lion Bioscience, AG
9.99 MathEcology LLC
9.100 Matrix Science
9.101 Medicel, Ltd.
9.102 METabolic EXplorer
9.103 Metahelix Life Sciences
9.104 Metalife
9.105 Monogram Biosciences, Inc.
9.106 Neurome, Inc.
9.107 Nonlinear Dynamics
9.108 Ocimum Biosolutions
9.109 OmniViz, Inc.
9.110 Partek Inc.
9.111 Perlegen Inc.
9.112 Prokaria
9.113 Quantiom Bioinformatics
9.114 Relevant Software, Inc.
9.115 Rosetta Inpharmatics
9.116 SBI Science LLC
9.117 Seascape Learning
9.118 Spotfire, U.S. Headquarters
9.119 Spotfire AB, European Headquarters
9.120 Spotfire, Japan Headquarters
9.121 Strand Life Sciences Pvt. Ltd.
9.122 Sun Microsystems
9.123 Syngene
9.124 Tahoe Informatics
9.125 3rd Millennium, Inc.
9.126 Thomson Scientific
9.127 TIB MOLBIOL
9.128 Tripos, Inc.
9.129 United Bioinformatica, Inc.
9.130 VizXLabs

INDEX OF FIGURES

Figure 4.1: Global Biotechnology Industry
Figure 5.1: Informatics Applications along the Drug-Discovery Value Chain
Figure 5.2: Functions of Bioinformatics Software in Research
Figure 5.3: Growth of GenBank, 1982-2002
Figure 5.4: EMBL Database Growth, 1991-2003
Figure 5.5: Steps Involved in Bringing a Drug to Market
Figure 5.6: Analysis of the Total Costs in Developing a New Drug
Figure 5.7: Role of Bioinformatics in the Biotechnology Value Chain
Figure 5.8: Worldwide Projected Pharmaceutical Sales and R&D Expenditure, 2000-2010
Figure 5.9: Worldwide Projected Growth in IT Budget, 2000-2010
Figure 5.10: Worldwide Projected Bioinformatics Market, 2000-2010
Figure 5.11: Worldwide Bioinformatics Market Vendor Components, 2000-2010
Figure 5.12: Steps of a Proteomics Experiment
Figure 5.13: Bioinformatics Architecture

INDEX OF TABLES

Table 2.1: Leading Biotechnology Companies
Table 2.2: Pharmaceutical R&D Expenditures by World Region, 1990-2003
Table 2.3: Total of Domestic U.S. R&D and R&D Abroad, Ethical Pharmaceuticals, Research-Based Pharmaceutical Companies, 1980-2003
Table 2.4: Global Pharmaceutical R&D Expenditures, 1993-2004
Table 2.5: SIB Informatics Databases
Table 4.1: The U.S. Biotechnology Industry Size and Revenue, 1995-2005
Table 4.2: Global Biotechnology Industry Major Segments
Table 4.3: Genomics Sector Market Size, 2001-2008
Table 4.4: The Biochip Array Market, 2000-2010
Table 4.5: Selected Competitors in the Biochip Market
Table 4.6: Biochip Microarray Products
Table 4.7: Bioinformatics Tools
Table 4.8: Functional Genomics Companies Building Advanced Integrated Platforms and Substantial Databases
Table 4.9: Companies Using New Genomic Tools
Table 4.10: Non-DNA Based Chip Suppliers
Table 4.11: Robotics or “Lab-on-a-Chip” Market Sector
Table 4.12: Key High-Throughput and Systemic Approaches for Genomic Analysis
Table 4.13: Total Biochip Market, 2002-2010
Table 4.14: Pharmacogenomics Segment Players
Table 4.15: The Worldwide Market for Pharmacogenomics, 2000-2008
Table 4.16: Competitors in the SNP Genotyping Segment
Table 4.17: Scanning and Detection Technology Suppliers
Table 5.1: Data Sources and Bioinformatic Investigations
Table 5.2: Drivers and Challenges of the Bioinformatics Industry
Table 5.3: Bioinformatics Activities, Sub-Activities and Key Players
Table 5.4: Alliances between IT/Telecom and Biotechnology Firms
Table 5.5: Types of Intellectual Property Protection for Bioinformatics Tools
Table 8.1: Bioinformatics Market Size, 2000-2010
Table 8.2: Cheminformatics Market Size, 2004-2010
Table 8.3: In-silico Informatics Market Size, 2004-2010
Table 8.4: Bioinformatics Hardware and Systems Market Size, 2004-2010