The Top 10 Generics Companies:


Strategic insight, growth opportunities and competitive dynamics in the US and Europe

Pages: 178

Publisher: Business Insights

Date Published: March 2006

Format: PDF

Price: Single User $2875

Price: Global / Enterprise $16000

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Overview

The generics sector has grown at a fast pace over the past few years, outperforming the pharmaceutical market as a whole; generic growth opportunities are significant, with an estimated $100bn worth of branded pharmaceutical products to go off patent by 2010, of which $21bn expire in 2006. Although US and major European generic drug sales increased rapidly from 2000 to 2003, there has been a slowdown in growth during 2004. In response to an increasingly competitive unbranded generic pharmaceutical marketplace, and a slowdown in growth in 2004, some of the major generics players have consolidated. The two largest M&A deals in the generics market in recent years have been the acquisition of Eon and HEXAL Labs by Sandoz in February 2005, and the acquisition of IVAX by Teva in January 2006. ‘The Top 10 Generics Companies: Strategic insight, growth opportunities and competitive dynamics in the US and Europe’, identifies the successful strategies utilized by the industry’s key players in the US and Western European market. The report provides insights into the top 10 generic companies strengths, weaknesses, opportunities and threats in the generic pharmaceutical market, allowing you to tailor the best practice strategies of the generic industry’s leading players to your company’s needs.

Table of Contents

Table of Contents

The Top 10 Generics Companies

Executive Summary

The generics market in US and Europe

Teva/IVAX

Sandoz (incl. Eon Labs and HEXAL)

Mylan

Ratiopharm

Watson Pharmaceuticals Inc.

Par Pharmaceuticals, Inc.

Merck KGaA

Baxter International Inc.

STADA

Apotex

Chapter 1 The generics market in the US and Europe

Summary

Introduction

Total generics market based on dollar sales

Western Europe

UK

Spain

Germany

France

Italy

US

Total generics market based on standard unit sales

The top 10 players

Geographic focus of the top 10

US

iv

5EU

Future geographic trends

Generics as a proportion of total sales of the top 10

Therapeutic focus of the top 10

Central nervous system

Cardiovascular system

General anti-infectives

Alimentary tract and metabolism

Key marketed products of the top 10

Key M&A activity

Sandoz/Eon/HEXAL

Teva/IVAX

Future outlook

Drivers of growth

FDA first approvals

Major upcoming patent expirations

Government influence and legislation

Medicare prescription drug plan

Resistors to growth

Competition between generics

Generic market maturity

Legislation enforcing generic drug pricing

FDA ANDA approval

Key strategies for growth

Chapter 2 Teva/IVAX

Summary

Company overview

Teva

IVAX

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

v

Chapter 3 Sandoz (incl. Eon Labs and HEXAL)

Summary

Company overview

Strategic analysis

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 4 Mylan

Summary

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 5 Ratiopharm

Ratiopharm

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

vi

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 6 Watson Pharmaceuticals Inc.

Summary

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 7 Par Pharmaceuticals, Inc.

Summary

Company overview

Strategic Position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 8 Merck KGaA

Summary

vii

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 9 Baxter International Inc.

Summary

Company overview

Strategic Position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 10 STADA

Summary

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

First generic FDA approvals, 2005

Therapeutic focus

M&A and licensing activity

viii

Chapter 11 Apotex

Summary

Company overview

Strategic position

Strengths

Weaknesses

Opportunities

Threats

Geographic focus

Marketed products

FDA first generic approvals, 2005

Therapeutic focus

M&A and licensing activity

Chapter 12 Appendix

IMS data

Index

List of Figures

Figure 1.1: Market share of the total generics market, 2004

Figure 1.2: Geographic focus of the top 10, 2004

Figure 1.3: Proportion of generic sales of the top 10, 2004

Figure 1.4: Market share of therapy areas in the US and major European generics pharmaceutical

market, 2003-4

Figure 1.5: Key drivers and resistors to sales growth in the US/5EU generic drug market

Figure 2.6: SWOT analysis for Teva/IVAX

Figure 2.7: Teva/IVAX’s geographic focus, 2003-4

Figure 2.8: Teva/IVAX’s therapeutic focus, 2004

Figure 3.9: SWOT analysis for Sandoz

Figure 3.10: Sandoz’s geographic focus, 2003-4

Figure 3.11: Sandoz’s therapeutic focus, 2004

Figure 4.12: SWOT analysis for Mylan

Figure 4.13: Mylan’s geographic focus, 2003-4

Figure 4.14: Mylan’s therapeutic focus, 2004

Figure 5.15: SWOT analysis for Ratiopharm

Figure 5.16: Ratiopharm’s geographic focus, 2003-4

Figure 5.17: Ratiopharm’s therapeutic focus, 2004

Figure 6.18: SWOT analysis for Watson

Figure 6.19: Watson’s geographic focus, 2003-4

Figure 6.20: Watson’s therapeutic focus, 2004

ix

Figure 7.21: SWOT analysis for Par

Figure 7.22: Par’s geographic focus, 2003-4

Figure 7.23: Par’s therapeutic focus, 2004

Figure 8.24: SWOT analysis for Merck KGaA

Figure 8.25: Merck KGaA’s geographic focus, 2003-4

Figure 8.26: Merck KGaA’s therapeutic focus, 2004

Figure 9.27: SWOT analysis for Baxter

Figure 9.28: Baxter’s geographic focus, 2003-4

Figure 9.29: Baxter’s therapeutic focus, 2004

Figure 10.30: SWOT analysis for STADA

Figure 10.31: STADA’s geographic focus, 2003-4

Figure 10.32: STADA’s therapeutic focus, 2004

Figure 11.33: SWOT analysis for Apotex

Figure 11.34: Apotex’s geographic focus, 2003-4

Figure 11.35: Apotex’s therapeutic focus, 2004

List of Tables

Table 1.1: Total generic sales in the US and 5EU, 2000-2004

Table 1.2: Total generic sales in the US and 5EU (standard units), 2000-2004

Table 1.3: Top 10 generics company sales in the US and 5EU, 2003-4

Table 1.4: Top 10 generics company sales in the US, 2003-4

Table 1.5: Top 10 generics company sales in the 5EU, 2003-4

Table 1.6: Largest therapy area based on 2004 sales ($m)

Table 1.7: Top 10 generics of the US and 5EU, 2004

Table 1.8: Patent expiration dates for the top selling generic drugs, US

Table 1.9: FDA first generic approvals, 2001-2005

Table 1.10: US patent expirations, 2006-7

Table 2.11: Teva/IVAX’s top 10 marketed products, 2004

Table 2.12: Teva/IVAX’s FDA first generic approvals, 2005

Table 2.13: Teva/IVAX’s key licensing and alliance activity, 2004-5

Table 3.14: Sandoz’s top 10 marketed products, 2004

Table 3.15: Sandoz’s FDA first generic approvals, 2005

Table 3.16: Sandoz’s key licensing and alliance activity, 2004-5

Table 4.17: Mylan’s top 10 marketed products, 2004

Table 4.18: Mylan’s FDA first generic approvals, 2005

Table 4.19: Mylan’s key licensing and alliance activity, 2004-5

Table 5.20: Ratiopharm’s top 10 marketed products, 2004